FUNCTSNP: AN R PACKAGE TO LINK SNPS TO FUNCTIONAL KNOWLEDGE AND DBAUTOMAKER: A SUITE OF PERL SCRIPTS TO BUILD SNP DATABASES

FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases

Abstract Background Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a particular complex trait of interest.One of the main outcomes from these studies is a subset of statistically significant SNPs.Finding the potential biological fun

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A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants

Large-scale populations in the world have been vaccinated with COVID-19 vaccines, however, breakthrough infections of SARS-CoV-2 are still growing rapidly due to the emergence of immune-evasive variants, especially Omicron.It is urgent to develop effective broad-spectrum vaccines to better control the pandemic of these variants.Here, we present a m

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The Landscape of Noncoding RNA in Pulmonary Hypertension

The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding RNA transcripts playing crucial roles.The majority of RNAs in the noncoding transcriptome are long noncoding Vases RNAs (lncRNAs) with less circular RNAs (circRNAs), which are two characteristics gaining increasing attention in the foref

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Physically Explainable Intelligent Perception and Application of SAR Target Characteristics Based on Time-frequency Analysis

The current state of intelligent target MENOSMART PLUS recognition approaches for Synthetic Aperture Radar (SAR) continues to experience challenges owing to their limited robustness, generalizability, and interpretability.Currently, research focuses on comprehending the microwave properties of SAR targets and integrating them with advanced deep lea

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